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2018 The Effect of Degradation on Cytotoxicity After Occluding of Dentin Tubules with Pure and Fluoride-Doped Nano-Hydroxyapatite

Abstract In recent years, many agents and methods have been employed for treating dentin hypersensitivity by occluding the dentinal tubules [1,2]. One of the biomaterials used in this occluding process is pure and differently doped nano-hydroxyapatite. For this purpose, pure and different rated F ions doped nano-hydroxyapatites, synthesized by the precipitation method [3,4], have been used for plugging in dentin tubules. At the end of the occluding process SEM, 1 - 2 - 3 - 4 weeks of degredation and pH study were performed to examine the physical properties changes. A degredation study was performed to observe coating efficiency for specimens samples after occluding. Moreover, after the degredation operation, cytotoxicity studies were carried out using MTT method on L929 fibroblast cells to investigate the toxic properties of degrade product in liquid SBF and degrade treatment at the end of the degredation study. All of the nHAp materials evaluated in this study formed an effective clogging layer in the dentin tubes. It is also found that this layer is resistant to degradation and does not cause toxicity.

International Symposium on Light Alloys and Composite Materials
UHAKS

Serdar BAGLAR Umit ERDEM Mustafa DOGAN

244 160
Subject Area: Chemistry Broadcast Area: International Type: Oral Paper Language: English